What Helps Curb the Side Effects of GLP-1 Weight Loss Medications?

Evidence-based strategies to curb nausea, constipation, and muscle loss

GLP-1 drugs like semaglutide and tirzepatide often cause nausea, constipation, and fatigue. Slow dose escalation, small frequent meals, hydration, and avoiding high-fat foods help most patients. For persistent nausea, non-serotonergic antiemetics may be used. Strength training and adequate protein help prevent muscle loss.